| Protein Name | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1 |
|---|---|
| Organism | Caenorhabditis elegans |
| Gene ID | 175502 |
| Gene Symbol | tir-1 |
| UniProt | Q86DA5 (SARM1_CAEEL), Q5I9W0 (Q5I9W0_CAEEL), A0A0K3ART9 (A0A0K3ART9_CAEEL) |
| Relationships |
Total Number of functionally related compound(s) :
13
Total Number of Articles : 10 |
Description |
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1 |
| Gene Summary |
Enables several functions, including NAD+ nucleosidase activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including NAD+ catabolic process; defense response to bacterium; and regulation of gene expression. Acts upstream of or within serotonin biosynthetic process. Located in axon cytoplasm and cell body. Is expressed in head; intestine; and pharynx. Used to study amyotrophic lateral sclerosis. Orthologous to human SARM1 (sterile alpha and TIR motif containing 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |