| Protein Name | Acetylcholine regulator unc-18 |
|---|---|
| Organism | Caenorhabditis elegans |
| Gene ID | 181030 |
| Gene Symbol | unc-18 |
| UniProt | P34815 (UNC18_CAEEL) |
| Relationships |
Total Number of functionally related compound(s) :
8
Total Number of Articles : 11 |
Description |
Acetylcholine regulator unc-18 |
| Gene Summary |
Enables syntaxin binding activity. Involved in cholinergic synaptic transmission; positive regulation of neurotransmitter secretion; and synaptic vesicle docking. Located in axon. Is expressed in intestine; nervous system; and uv1. Used to study alcohol use disorder and developmental and epileptic encephalopathy. Human ortholog(s) of this gene implicated in West syndrome; developmental and epileptic encephalopathy 4; and familial hemophagocytic lymphohistiocytosis 5. Orthologous to several human genes including STXBP1 (syntaxin binding protein 1). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |