Protein Name AcetylCholine Receptor
Organism Caenorhabditis elegans
Gene ID 191605
Gene Symbol

acr-19

UniProt G5EGB5 (G5EGB5_CAEEL), B3WFZ2 (B3WFZ2_CAEEL)
Relationships Total Number of functionally related compound(s) : 1
Total Number of Articles : 1
Description

AcetylCholine Receptor

Gene Summary

Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in chemical synaptic transmission; monoatomic ion transmembrane transport; and regulation of membrane potential. Predicted to be located in postsynaptic membrane. Predicted to be part of acetylcholine-gated channel complex. Predicted to be active in neuron projection; plasma membrane; and synapse. Used to study nicotine dependence. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease; esophagus squamous cell carcinoma; respiratory system cancer (multiple); and schizophrenia. Orthologous to human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • AcetylCholine Receptor
  • CELE_C31H5.3
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Properties