| Protein Name | actin, alpha, cardiac muscle 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 29275 |
| Gene Symbol | Actc1 |
| UniProt | P68035 (ACTC_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
5
Total Number of Articles : 6 |
Description |
actin, alpha, cardiac muscle 1 |
| Gene Summary |
Predicted to enable ATP binding activity; microfilament motor activity; and myosin binding activity. Involved in cardiac muscle contraction; response to ethanol; and response to xenobiotic stimulus. Predicted to be located in several cellular components, including I band; filopodium; and lamellipodium. Predicted to be part of protein-containing complex. Predicted to be active in actin filament; glutamatergic synapse; and sarcomere. Biomarker of hypertension. Human ortholog(s) of this gene implicated in atrial heart septal defect 5; dilated cardiomyopathy; dilated cardiomyopathy 1R; and hypertrophic cardiomyopathy 11. Orthologous to human ACTC1 (actin alpha cardiac muscle 1). [provided by Alliance of Genome Resources, Jul 2025] |
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