| Protein Name | glypican 3 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25236 |
| Gene Symbol | Gpc3 |
| UniProt | P13265 (GPC3_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
12
Total Number of Articles : 9 |
Description |
glypican 3 |
| Gene Summary |
Predicted to enable peptidyl-dipeptidase inhibitor activity. Acts upstream of or within negative regulation of canonical Wnt signaling pathway and positive regulation of Wnt signaling pathway, planar cell polarity pathway. Located in plasma membrane. Used to study hepatocellular carcinoma. Human ortholog(s) of this gene implicated in Simpson-Golabi-Behmel syndrome type 1 and nephroblastoma. Orthologous to human GPC3 (glypican 3). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |