Protein Name B52
Organism Drosophila melanogaster
Gene ID 41670
Gene Symbol


UniProt P26686 (SRR55_DROME), A0A0C4DHG5 (A0A0C4DHG5_DROME)
Relationships Total Number of functionally related compound(s) : 3
Total Number of Articles : 2


Gene Summary

Enables mRNA binding activity. Involved in several processes, including defense response to virus; mitotic G1/S transition checkpoint signaling; and regulation of RNA metabolic process. Located in nuclear speck; polytene chromosome; and transcriptionally active chromatin. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in several structures, including adult head; adult heart; embryonic brain; and embryonic/larval neurons. Human ortholog(s) of this gene implicated in proliferative diabetic retinopathy and spermatogenic failure 3. Orthologous to several human genes including SRSF4 (serine and arginine rich splicing factor 4) and SRSF6 (serine and arginine rich splicing factor 6). [provided by Alliance of Genome Resources, Apr 2022]

  • B52
  • B52-PA
  • B52-PB
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