Protein Name derailed
Organism Drosophila melanogaster
Gene ID 44355
Gene Symbol

drl

UniProt Q27324 (RYK1_DROME), M9PDD9 (M9PDD9_DROME)
Relationships Total Number of functionally related compound(s) : 4
Total Number of Articles : 4
Description

derailed

Gene Summary

Enables several functions, including Wnt receptor activity; Wnt-protein binding activity; and protein dimerization activity. Involved in several processes, including determination of muscle attachment site; learning or memory; and neuron projection guidance. Located in axon; dendrite; and plasma membrane. Part of receptor complex. Is expressed in several structures, including A1-7 lateral transverse muscle cell; anlage in statu nascendi; brain; head epidermis primordium; and synaptic neuropil subdomain. Used to study intellectual disability. Orthologous to human RYK (receptor like tyrosine kinase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • derailed
  • CG17348-PA
  • CG17348-PB
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Properties