Protein Name superoxide dismutase 1
Organism Rattus norvegicus
Gene ID 24786
Gene Symbol


UniProt P07632 (SODC_RAT)
Relationships Total Number of functionally related compound(s) : 457
Total Number of Articles : 651

superoxide dismutase 1

Gene Summary

Enables copper ion binding activity; protein phosphatase 2B binding activity; and superoxide dismutase activity. Involved in several processes, including cellular response to metal ion; hydrogen peroxide biosynthetic process; and removal of superoxide radicals. Located in several cellular components, including dense core granule; mitochondrial intermembrane space; and neuronal cell body. Part of protein-containing complex. Used to study hyperthyroidism; hypothyroidism; middle cerebral artery infarction; and sciatic neuropathy. Biomarker of several diseases, including artery disease (multiple); congenital diaphragmatic hernia; middle cerebral artery infarction; non-alcoholic steatohepatitis; and ocular hypertension. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; artery disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); and neurodegenerative disease (multiple). Orthologous to human SOD1 (superoxide dismutase 1). [provided by Alliance of Genome Resources, Apr 2022]

  • superoxide dismutase [Cu-Zn]
  • superoxide dismutase 1, soluble
  • CuZnSOD
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