Protein Name adenosine kinase
Organism Mus musculus
Gene ID 11534
Gene Symbol

Adk

UniProt P55264 (ADK_MOUSE), Q8BMC5 (Q8BMC5_MOUSE)
Relationships Total Number of functionally related compound(s) : 48
Total Number of Articles : 65
Description

adenosine kinase

Gene Summary

Enables adenosine kinase activity and deoxyadenosine kinase activity. Involved in AMP salvage; GMP salvage; and dAMP salvage. Acts upstream of or within dATP biosynthetic process and purine ribonucleoside salvage. Located in cytosol and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeleton. Used to study fatty liver disease. Human ortholog(s) of this gene implicated in hypermethioninemia due to adenosine kinase deficiency. Orthologous to human ADK (adenosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • adenosine kinase
  • adenosine 5'-phosphotransferase
  • 2310026J05Rik
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Properties