Protein Name peptidoglycan recognition protein 1
Organism Mus musculus
Gene ID 21946
Gene Symbol

Pglyrp1

UniProt O88593 (PGRP1_MOUSE), Q4FK86 (Q4FK86_MOUSE)
Relationships Total Number of functionally related compound(s) : 7
Total Number of Articles : 6
Description

peptidoglycan recognition protein 1

Gene Summary

Predicted to enable several functions, including Hsp70 protein binding activity; peptidoglycan binding activity; and peptidoglycan immune receptor activity. Acts upstream of or within several processes, including negative regulation of inflammatory response; negative regulation of natural killer cell differentiation involved in immune response; and negative regulation of type II interferon production. Predicted to be located in cytoplasm and extracellular region. Predicted to be active in extracellular space. Is expressed in alimentary system; craniocervical region bone; genitourinary system; liver; and respiratory system. Orthologous to human PGLYRP1 (peptidoglycan recognition protein 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • peptidoglycan recognition protein 1
  • cytokine tag7
  • PGRP
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Properties