| Protein Name | myotubularin related protein 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 77116 |
| Gene Symbol | Mtmr2 |
| UniProt | Q9Z2D1 (MTMR2_MOUSE), Q6P572 (Q6P572_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
8
Total Number of Articles : 10 |
Description |
myotubularin related protein 2 |
| Gene Summary |
Enables identical protein binding activity; phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity; and phosphatidylinositol-3-phosphate phosphatase activity. Acts upstream of or within negative regulation of myelination; nervous system development; and phosphatidylinositol dephosphorylation. Located in vacuolar membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Used to study Charcot-Marie-Tooth disease type 4B1. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4B1. Orthologous to human MTMR2 (myotubularin related protein 2). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |