Protein Name fibrinogen alpha chain
Organism Rattus norvegicus
Gene ID 361969
Gene Symbol

Fga

UniProt Q7TQ70 (Q7TQ70_RAT), A1L114 (A1L114_RAT)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 4
Description

fibrinogen alpha chain

Gene Summary

Predicted to enable protein-macromolecule adaptor activity and structural molecule activity. Predicted to contribute to cell adhesion molecule binding activity and signaling receptor binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to phorbol 13-acetate 12-myristate; and liver regeneration. Located in blood microparticle. Used to study asthma; brain ischemia; disseminated intravascular coagulation; and thrombocytopenia. Biomarker of acute kidney failure; artery disease (multiple); disseminated intravascular coagulation; pancreatitis; and pulmonary emphysema. Human ortholog(s) of this gene implicated in brain small vessel disease; congenital afibrinogenemia; familial visceral amyloidosis; and thrombophilia. Orthologous to human FGA (fibrinogen alpha chain). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • fibrinogen alpha chain
  • fibrinogen, A alpha polypeptide
  • fibrinogen, alpha polypeptide
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Properties