CPRiL

Protein Name	sodium channel epithelial 1 subunit beta
Organism	Rattus norvegicus
Gene ID	24767
Gene Symbol	Scnn1b
UniProt	P37090 (SCNNB_RAT), B8QP48 (B8QP48_RAT)
Relationships	Total Number of functionally related compound(s) : 14 Total Number of Articles : 13
Description	sodium channel epithelial 1 subunit beta
Gene Summary	Enables WW domain binding activity and ligand-gated sodium channel activity. Contributes to sodium ion transmembrane transporter activity. Involved in several processes, including intracellular sodium ion homeostasis; sodium ion import across plasma membrane; and wound healing, spreading of epidermal cells. Located in apical plasma membrane and cell surface. Used to study nephrotic syndrome. Human ortholog(s) of this gene implicated in Liddle syndrome; bronchiectasis 1; and pseudohypoaldosteronism. Orthologous to human SCNN1B (sodium channel epithelial 1 subunit beta). [provided by Alliance of Genome Resources, Jun 2025]
synonyms	epithelial sodium channel subunit beta amiloride-sensitive sodium channel subunit beta SCNEB beta-ENaC beta-NaCH epithelial Na(+) channel subunit beta nonvoltage-gated sodium channel 1 subunit beta sodium channel epithelial 1 beta subunit sodium channel, non-voltage-gated 1, beta subunit sodium channel, nonvoltage-gated, type I, beta RNENACB Click to show/hide the synonyms
Properties