Protein Name ATP-binding cassette, sub-family A member 2
Organism Mus musculus
Gene ID 11305
Gene Symbol

Abca2

UniProt A2AJ26 (A2AJ26_MOUSE)
Relationships Total Number of functionally related compound(s) : 14
Total Number of Articles : 7
Description

ATP-binding cassette, sub-family A member 2

Gene Summary

Predicted to enable several functions, including ATP binding activity; ceramide floppase activity; and endopeptidase regulator activity. Involved in several processes, including regulation of intracellular cholesterol transport; regulation of protein localization; and sphingolipid metabolic process. Acts upstream of or within central nervous system myelin formation. Located in lysosomal membrane. Is expressed in brain; retina; and spinal cord. Orthologous to human ABCA2 (ATP binding cassette subfamily A member 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • ATP-binding cassette sub-family A member 2
  • ATP-binding cassette 2
  • ATP-binding cassette transporter 2
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Properties