| Protein Name | AcetylCholine Receptor |
|---|---|
| Organism | Caenorhabditis elegans |
| Gene ID | 181246 |
| Gene Symbol | acr-8 |
| UniProt | - |
| Relationships |
Total Number of functionally related compound(s) :
6
Total Number of Articles : 4 |
Description |
AcetylCholine Receptor |
| Gene Summary |
Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in several processes, including chemical synaptic transmission; inorganic cation transmembrane transport; and monoatomic ion transmembrane transport. Predicted to be located in postsynaptic membrane. Predicted to be part of acetylcholine-gated channel complex. Predicted to be active in neuron projection; plasma membrane; and synapse. Is expressed in body wall musculature; enteric muscle; nerve ring; neurons; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; autosomal dominant nocturnal frontal lobe epilepsy (multiple); cocaine abuse; congenital myasthenic syndrome (multiple); and respiratory system cancer (multiple). Orthologous to several human genes including CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit); CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit); and CHRNA4 (cholinergic receptor nicotinic alpha 4 subunit). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |