Protein Name amyloid beta precursor protein binding family B member 3
Organism Homo sapiens
Gene ID 10307
Gene Symbol

APBB3

UniProt O95704 (APBB3_HUMAN), Q96DX9 (Q96DX9_HUMAN), Q59EH2 (Q59EH2_HUMAN)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 7
Description

amyloid beta precursor protein binding family B member 3

Gene Summary

The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • amyloid-beta A4 precursor protein-binding family B member 3
  • FE65-like protein 2
  • amyloid beta (A4) precursor protein-binding, family B, member 3
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Properties