Protein Name NK2 homeobox 5 S homeolog
Organism Xenopus laevis
Gene ID 379882
Gene Symbol

nkx2-5.S

UniProt Q7T0T3 (Q7T0T3_XENLA)
Relationships Total Number of functionally related compound(s) : 4
Total Number of Articles : 4
Description

NK2 homeobox 5 S homeolog

Gene Summary

Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of protein-DNA complex. Is expressed in cardiovascular system; endoderm; mesoderm; and musculoskeletal system. Human ortholog(s) of this gene implicated in aortic valve disease 2; atrioventricular block; congenital heart disease (multiple); and congenital nongoitrous hypothyroidism 5. Orthologous to human NKX2-5 (NK2 homeobox 5). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • homeobox protein Nkx-2.5
  • NK2 transcription factor related 5 b
  • NK2 transcription factor related, locus 5
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Properties