| Protein Name | SPG11, spatacsin vesicle trafficking associated |
|---|---|
| Organism | Mus musculus |
| Gene ID | 214585 |
| Gene Symbol | Spg11 |
| UniProt | Q3UHA3 (SPTCS_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
3
Total Number of Articles : 2 |
Description |
SPG11, spatacsin vesicle trafficking associated |
| Gene Summary |
Predicted to enable protein kinase binding activity. Acts upstream of or within several processes, including axonogenesis; cholesterol efflux; and transport along microtubule. Located in several cellular components, including axon; cytosol; and dendrite. Is active in endoplasmic reticulum. Used to study hereditary spastic paraplegia 11. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2X; amyotrophic lateral sclerosis type 5; and hereditary spastic paraplegia 11. Orthologous to human SPG11 (SPG11 vesicle trafficking associated, spatacsin). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |