| Protein Name | methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase |
|---|---|
| Organism | Mus musculus |
| Gene ID | 108156 |
| Gene Symbol | Mthfd1 |
| UniProt | Q922D8 (C1TC_MOUSE), Q8BXX7 (Q8BXX7_MOUSE), Q3TW74 (Q3TW74_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
25
Total Number of Articles : 15 |
Description |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase |
| Gene Summary |
This gene encodes a trifunctional cytoplasmic enzyme. The encoded protein functions as a methylenetetrahydrofolate dehydrogenase, a methenyltetrahydrofolate cyclohydrolase, and a formyltetrahydrofolate synthase. The encoded enzyme functions in de novo synthesis of purines and thymidylate and in regeneration of methionine from homocysteine. [provided by RefSeq, Oct 2009] |
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| Properties | |