| Protein Name | 7-dehydrocholesterol reductase |
|---|---|
| Organism | Danio rerio |
| Gene ID | 378446 |
| Gene Symbol | dhcr7 |
| UniProt | Q7SXF1 (DHCR7_DANRE) |
| Relationships |
Total Number of functionally related compound(s) :
3
Total Number of Articles : 3 |
Description |
7-dehydrocholesterol reductase |
| Gene Summary |
Enables oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor. Acts upstream of or within several processes, including behavioral fear response; cholesterol biosynthetic process; and neuron cellular homeostasis. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in alar plate midbrain region; digestive system; nervous system; and optic vesicle. Used to study Smith-Lemli-Opitz syndrome. Human ortholog(s) of this gene implicated in Behcet's disease and Smith-Lemli-Opitz syndrome. Orthologous to human DHCR7 (7-dehydrocholesterol reductase). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |