Protein Name tripeptidyl peptidase 1
Organism Rattus norvegicus
Gene ID 83534
Gene Symbol

Tpp1

UniProt Q9EQV6 (TPP1_RAT), Q642E6 (Q642E6_RAT)
Relationships Total Number of functionally related compound(s) : 19
Total Number of Articles : 6
Description

tripeptidyl peptidase 1

Gene Summary

Enables endopeptidase activity; peptide binding activity; and tripeptidyl-peptidase activity. Involved in protein catabolic process. Predicted to be located in several cellular components, including lysosome; membrane raft; and recycling endosome. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 7 and neuronal ceroid lipofuscinosis 2. Orthologous to human TPP1 (tripeptidyl peptidase 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • tripeptidyl-peptidase 1
  • TPP-1
  • TPP-I
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Properties