Protein Name H2B clustered histone 14
Organism Homo sapiens
Gene ID 8342
Gene Symbol

H2BC14

UniProt Q99879 (H2B1M_HUMAN)
Relationships Total Number of functionally related compound(s) : 1
Total Number of Articles : 1
Description

H2B clustered histone 14

Gene Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]

synonyms
  • histone H2B type 1-M
  • H2B histone family, member E
  • histone 1, H2bm
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Properties