| Protein Name | microsomal triglyceride transfer protein |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 310900 |
| Gene Symbol | Mttp |
| UniProt | D4A1W8 (MTP_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
100
Total Number of Articles : 68 |
Description |
microsomal triglyceride transfer protein |
| Gene Summary |
Enables apolipoprotein binding activity and lipid transfer activity. Involved in several processes, including cholesterol homeostasis; lipoprotein metabolic process; and response to calcium ion. Located in several cellular components, including basolateral plasma membrane; cell projection membrane; and rough endoplasmic reticulum. Biomarker of familial hyperlipidemia. Human ortholog(s) of this gene implicated in several diseases, including abdominal obesity-metabolic syndrome 1; abetalipoproteinemia; familial hypercholesterolemia; hyperinsulinism; and obesity. Orthologous to human MTTP (microsomal triglyceride transfer protein). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |