Protein Name sucrase-isomaltase
Organism Rattus norvegicus
Gene ID 497756
Gene Symbol

Si

UniProt P23739 (SUIS_RAT)
Relationships Total Number of functionally related compound(s) : 43
Total Number of Articles : 45
Description

sucrase-isomaltase

Gene Summary

Enables beta-fructofuranosidase activity and oligo-1,6-glucosidase activity. Involved in several processes, including carbohydrate utilization; intestinal epithelial cell maturation; and response to cortisone. Located in several cellular components, including Golgi cisterna; cell projection membrane; and multivesicular body. Biomarker of colitis and exocrine pancreatic insufficiency. Human ortholog(s) of this gene implicated in congenital sucrase-isomaltase deficiency. Orthologous to human SI (sucrase-isomaltase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • sucrase-isomaltase, intestinal
  • sucrase-isomaltase (alpha-glucosidase)
  • SUCIMAL
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Properties