Protein Name estrogen receptor 1
Organism Xenopus tropicalis
Gene ID 394461
Gene Symbol

esr1

UniProt Q6W5G9 (Q6W5G9_XENTR)
Relationships Total Number of functionally related compound(s) : 4
Total Number of Articles : 5
Description

estrogen receptor 1

Gene Summary

Predicted to enable estrogen response element binding activity and nuclear receptor activity. Predicted to be involved in cellular response to estrogen stimulus; estrogen receptor signaling pathway; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription and steroid hormone receptor signaling pathway. Predicted to be active in chromatin and nucleus. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); bone disease (multiple); breast cancer (multiple); type 2 diabetes mellitus; and vitiligo. Orthologous to human ESR1 (estrogen receptor 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • estrogen receptor
  • estrogen receptor alpha
  • ERalpha
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Properties