Protein Name steroid 5 alpha-reductase 2
Organism Xenopus tropicalis
Gene ID 549867
Gene Symbol

srd5a2

UniProt A0A6I8PNY4 (A0A6I8PNY4_XENTR)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 4
Description

steroid 5 alpha-reductase 2

Gene Summary

Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in androgen biosynthetic process and male gonad development. Predicted to act upstream of or within cell differentiation; sex differentiation; and steroid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in neuronal cell body. Is expressed in cardiovascular system; ectoderm; liver and biliary system; nervous system; and vestibuloauditory system. Human ortholog(s) of this gene implicated in hypospadias and prostate cancer. Orthologous to human SRD5A2 (steroid 5 alpha-reductase 2). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • 3-oxo-5-alpha-steroid 4-dehydrogenase 2
  • steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • SRD5alpha2
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Properties