| Protein Name | protoporphyrinogen oxidase |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19044 |
| Gene Symbol | Ppox |
| UniProt | P51175 (PPOX_MOUSE), Q3UQA3 (Q3UQA3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
52
Total Number of Articles : 34 |
Description |
protoporphyrinogen oxidase |
| Gene Summary |
Enables oxygen-dependent protoporphyrinogen oxidase activity. Involved in heme A biosynthetic process and heme B biosynthetic process. Acts upstream of or within heme biosynthetic process. Located in mitochondrial inner membrane. Is active in mitochondrial intermembrane space. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Used to study variegate porphyria. Human ortholog(s) of this gene implicated in variegate porphyria. Orthologous to human PPOX (protoporphyrinogen oxidase). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |