Protein Name AAA family ATPase peroxin 1
Organism Saccharomyces cerevisiae S288C
Gene ID 853636
Gene Symbol

PEX1

UniProt P24004 (PEX1_YEAST)
Relationships Total Number of functionally related compound(s) : 13
Total Number of Articles : 16
Description

AAA family ATPase peroxin 1

Gene Summary

Enables ATP hydrolysis activity. Involved in protein import into peroxisome matrix, receptor recycling and protein unfolding. Located in peroxisomal membrane. Part of ATPase complex and transporter complex. Used to study Zellweger syndrome and peroxisomal biogenesis disorder. Human ortholog(s) of this gene implicated in Heimler syndrome 1; Zellweger syndrome; peroxisome biogenesis disorder 1A; and peroxisome biogenesis disorder 1B. Orthologous to human PEX1 (peroxisomal biogenesis factor 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • AAA family ATPase peroxin 1
  • YKL197C
  • PAS1
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Properties