Protein Name fumarylacetoacetate hydrolase
Organism Rattus norvegicus
Gene ID 29383
Gene Symbol

Fah

UniProt P25093 (FAAA_RAT)
Relationships Total Number of functionally related compound(s) : 14
Total Number of Articles : 12
Description

fumarylacetoacetate hydrolase

Gene Summary

Predicted to enable fumarylacetoacetase activity. Predicted to be involved in L-phenylalanine catabolic process; L-tyrosine catabolic process; and homogentisate catabolic process. Predicted to act upstream of or within L-arginine catabolic process. Used to study liver cirrhosis and tyrosinemia type I. Biomarker of hypertension. Human ortholog(s) of this gene implicated in tyrosinemia type I. Orthologous to human FAH (fumarylacetoacetate hydrolase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • fumarylacetoacetase
  • FAA
  • beta-diketonase
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Properties