| Protein Name | sorting nexin 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6642 |
| Gene Symbol | SNX1 |
| UniProt | Q13596 (SNX1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
18
Total Number of Articles : 16 |
Description |
sorting nexin 1 |
| Gene Summary |
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
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| Properties | |