Protein Name cadherin, EGF LAG seven-pass G-type receptor 2
Organism Mus musculus
Gene ID 53883
Gene Symbol

Celsr2

UniProt Q9R0M0 (CELR2_MOUSE)
Relationships Total Number of functionally related compound(s) : 7
Total Number of Articles : 5
Description

cadherin, EGF LAG seven-pass G-type receptor 2

Gene Summary

Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Involved in several processes, including Wnt signaling pathway; homophilic cell adhesion via plasma membrane adhesion molecules; and neural plate anterior/posterior regionalization. Acts upstream of or within several processes, including cerebrospinal fluid secretion; cilium assembly; and nervous system development. Located in cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; skin; and visual system. Used to study hydrocephalus. Orthologous to human CELSR2 (cadherin EGF LAG seven-pass G-type receptor 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • cadherin EGF LAG seven-pass G-type receptor 2
  • cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
  • flamingo homolog
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Properties