Protein Name vav 2 oncogene
Organism Mus musculus
Gene ID 22325
Gene Symbol

Vav2

UniProt Q60992 (VAV2_MOUSE), Q7TSI6 (Q7TSI6_MOUSE)
Relationships Total Number of functionally related compound(s) : 16
Total Number of Articles : 15
Description

vav 2 oncogene

Gene Summary

This gene encodes a member of the Vav family of Rho guanine nucleotide exchange factors. Vav family proteins are involved in the development and activation of lymphocytes, and the encoded protein may also be involved in angiogenesis. Disruption of this gene in mice is associated with heart, artery, and kidney defects, as well as tachycardia and hypertension. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

synonyms
  • guanine nucleotide exchange factor VAV2
  • 2810040F13Rik
  • Vav-2
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Properties