Protein Name monothiol glutaredoxin GRX5
Organism Saccharomyces cerevisiae S288C
Gene ID 856048
Gene Symbol

GRX5

UniProt Q02784 (GLRX5_YEAST)
Relationships Total Number of functionally related compound(s) : 28
Total Number of Articles : 29
Description

monothiol glutaredoxin GRX5

Gene Summary

Enables 2 iron, 2 sulfur cluster binding activity and disulfide oxidoreductase activity. Involved in cellular response to oxidative stress; iron-sulfur cluster assembly; and response to osmotic stress. Located in mitochondrial matrix. Human ortholog(s) of this gene implicated in autosomal recessive pyridoxine-refractory sideroblastic anemia 3. Orthologous to human GLRX5 (glutaredoxin 5). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • monothiol glutaredoxin GRX5
  • YPL059W
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Properties