Protein Name Fe-binding Fe/S cluster assembly protein ISA1
Organism Saccharomyces cerevisiae S288C
Gene ID 850632
Gene Symbol

ISA1

UniProt Q07821 (ISA1_YEAST)
Relationships Total Number of functionally related compound(s) : 9
Total Number of Articles : 6
Description

Fe-binding Fe/S cluster assembly protein ISA1

Gene Summary

Enables iron ion binding activity. Involved in biotin biosynthetic process; iron-sulfur cluster assembly; and protein maturation by [4Fe-4S] cluster transfer. Located in mitochondrial matrix. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 5. Orthologous to human ISCA1 (iron-sulfur cluster assembly 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • Fe-binding Fe/S cluster assembly protein ISA1
  • YLL027W
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Properties