Protein Name cyclin dependent kinase 11B
Organism Homo sapiens
Gene ID 984
Gene Symbol

CDK11B

UniProt P21127 (CD11B_HUMAN), B4DII1 (B4DII1_HUMAN)
Relationships Total Number of functionally related compound(s) : 49
Total Number of Articles : 40
Description

cyclin dependent kinase 11B

Gene Summary

This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

synonyms
  • cyclin-dependent kinase 11B
  • CDC-related protein kinase p58
  • PITSLRE serine/threonine-protein kinase CDC2L1
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Properties