Protein Name N-alpha-acetyltransferase 10, NatA catalytic subunit
Organism Homo sapiens
Gene ID 8260
Gene Symbol

NAA10

UniProt P41227 (NAA10_HUMAN), B7Z9N2 (B7Z9N2_HUMAN)
Relationships Total Number of functionally related compound(s) : 101
Total Number of Articles : 90
Description

N-alpha-acetyltransferase 10, NatA catalytic subunit

Gene Summary

N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes an N-terminal acetyltransferase that functions as the catalytic subunit of the major amino-terminal acetyltransferase A complex. Mutations in this gene are the cause of Ogden syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

synonyms
  • N-alpha-acetyltransferase 10
  • ARD1 homolog A, N-acetyltransferase
  • N-acetyltransferase ARD1, human homolog of
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Properties