Protein Name potassium voltage-gated channel subfamily A member 6
Organism Homo sapiens
Gene ID 3742
Gene Symbol

KCNA6

UniProt P17658 (KCNA6_HUMAN)
Relationships Total Number of functionally related compound(s) : 10
Total Number of Articles : 9
Description

potassium voltage-gated channel subfamily A member 6

Gene Summary

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class. The coding region of this gene is intronless, and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12. [provided by RefSeq, Jul 2008]

synonyms
  • potassium voltage-gated channel subfamily A member 6
  • human brain potassium channel-2
  • potassium channel, voltage gated shaker related subfamily A, member 6
Click to show/hide the synonyms
Properties