Protein Name cystathionine gamma-lyase
Organism Rattus norvegicus
Gene ID 24962
Gene Symbol

Cth

UniProt P18757 (CGL_RAT), Q9EQS4 (Q9EQS4_RAT)
Relationships Total Number of functionally related compound(s) : 167
Total Number of Articles : 240
Description

cystathionine gamma-lyase

Gene Summary

Predicted to enable carbon-sulfur lyase activity; identical protein binding activity; and pyridoxal phosphate binding activity. Involved in glutathione metabolic process; negative regulation of cell growth; and negative regulation of cell population proliferation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Used to study cataract. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and cystathioninuria. Orthologous to human CTH (cystathionine gamma-lyase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • cystathionine gamma-lyase
  • CTL target antigen
  • PRB-RA
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Properties