Protein Name 5-methyltetrahydrofolate-homocysteine methyltransferase
Organism Mus musculus
Gene ID 238505
Gene Symbol

Mtr

UniProt A6H5Y3 (METH_MOUSE)
Relationships Total Number of functionally related compound(s) : 18
Total Number of Articles : 21
Description

5-methyltetrahydrofolate-homocysteine methyltransferase

Gene Summary

Enables methionine synthase activity. Acts upstream of or within methionine biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including eye; genitourinary system; integumental system; limb; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; hematologic cancer (multiple); hyperhomocysteinemia; and methylmalonic aciduria and homocystinuria type cblG. Orthologous to human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • methionine synthase
  • cobalamin-dependent methionine synthase
  • vitamin-B12 dependent methionine synthase
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Properties