| Protein Name | trifunctional aldehyde reductase/xylose reductase/glucose 1-dehydrogenase (NADP(+)) |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 856504 |
| Gene Symbol | GRE3 |
| UniProt | P38715 (GRE3_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
24
Total Number of Articles : 27 |
Description |
trifunctional aldehyde reductase/xylose reductase/glucose 1-dehydrogenase (NADP(+)) |
| Gene Summary |
Enables D-xylose reductase (NADPH) activity and mRNA binding activity. Involved in cellular response to osmotic stress; cellular response to oxidative stress; and monosaccharide catabolic process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in 46,XY sex reversal 8; alcohol dependence; congenital bile acid synthesis defect 2; and leukemia (multiple). Orthologous to several human genes including AKR1E2 (aldo-keto reductase family 1 member E2). [provided by Alliance of Genome Resources, Jun 2025] |
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