| Protein Name | H(+)-transporting V0 sector ATPase subunit a |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 855076 |
| Gene Symbol | STV1 |
| UniProt | P37296 (STV1_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
7
Total Number of Articles : 5 |
Description |
H(+)-transporting V0 sector ATPase subunit a |
| Gene Summary |
Enables phosphatidylinositol-4-phosphate binding activity. Contributes to proton-transporting ATPase activity, rotational mechanism. Involved in vacuolar acidification. Located in Golgi apparatus and late endosome. Part of vacuolar proton-transporting V-type ATPase, V0 domain. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIA; autosomal recessive osteopetrosis 1; developmental and epileptic encephalopathy 104; renal tubular acidosis; and wrinkly skin syndrome. Orthologous to several human genes including ATP6V0A1 (ATPase H+ transporting V0 subunit a1); ATP6V0A2 (ATPase H+ transporting V0 subunit a2); and ATP6V0A4 (ATPase H+ transporting V0 subunit a4). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |