Protein Name WW, C2 and coiled-coil domain containing 1
Organism Mus musculus
Gene ID 211652
Gene Symbol

Wwc1

UniProt Q5SXA9 (KIBRA_MOUSE)
Relationships Total Number of functionally related compound(s) : 5
Total Number of Articles : 5
Description

WW, C2 and coiled-coil domain containing 1

Gene Summary

Predicted to enable kinase binding activity; signaling adaptor activity; and transcription coactivator activity. Predicted to be involved in several processes, including negative regulation of organ growth; negative regulation of transcription by RNA polymerase II; and regulation of intracellular signal transduction. Predicted to act upstream of or within hippo signaling and positive regulation of hippo signaling. Located in cytoplasm. Is expressed in cerebral cortex; female associated reproductive structure; forelimb bud ectoderm; primitive collecting duct; and retina. Orthologous to human WWC1 (WW and C2 domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • protein KIBRA
  • WW domain-containing protein 1
  • kidney and brain protein
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Properties