Protein Name phosphodiesterase 3B
Organism Rattus norvegicus
Gene ID 29516
Gene Symbol

Pde3b

UniProt Q63085 (PDE3B_RAT)
Relationships Total Number of functionally related compound(s) : 34
Total Number of Articles : 34
Description

phosphodiesterase 3B

Gene Summary

Enables 3',5'-cyclic-AMP phosphodiesterase activity; 3',5'-cyclic-GMP phosphodiesterase activity; and phosphoprotein binding activity. Involved in negative regulation of cAMP/PKA signal transduction and negative regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Predicted to be part of guanyl-nucleotide exchange factor complex. Orthologous to human PDE3B (phosphodiesterase 3B). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B
  • CGI-PDE B
  • CGIPDE1
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Properties