| Protein Name | arginase type II |
|---|---|
| Organism | Mus musculus |
| Gene ID | 11847 |
| Gene Symbol | Arg2 |
| UniProt | O08691 (ARGI2_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
99
Total Number of Articles : 90 |
Description |
arginase type II |
| Gene Summary |
Predicted to enable arginase activity; manganese ion binding activity; and nitric-oxide synthase binding activity. Involved in several processes, including negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process; and negative regulation of cytokine production. Acts upstream of or within striated muscle contraction. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ARG2 (arginase 2). [provided by Alliance of Genome Resources, Jun 2025] |
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