| Protein Name | 3-ketodihydrosphingosine reductase |
|---|---|
| Organism | Danio rerio |
| Gene ID | 394114 |
| Gene Symbol | kdsr |
| UniProt | F1QWW8 (F1QWW8_DANRE) |
| Relationships |
Total Number of functionally related compound(s) :
1
Total Number of Articles : 2 |
Description |
3-ketodihydrosphingosine reductase |
| Gene Summary |
Predicted to enable 3-dehydrosphinganine reductase activity and NADPH binding activity. Acts upstream of or within several processes, including intracellular sphingolipid homeostasis; platelet formation; and sphingomyelin biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Used to study liver disease and thrombocytopenia. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis et progressiva 4 and follicular lymphoma. Orthologous to human KDSR (3-ketodihydrosphingosine reductase). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |