Protein Name solute carrier family 38, member 3
Organism Mus musculus
Gene ID 76257
Gene Symbol

Slc38a3

UniProt Q9DCP2 (S38A3_MOUSE)
Relationships Total Number of functionally related compound(s) : 89
Total Number of Articles : 61
Description

solute carrier family 38, member 3

Gene Summary

Enables L-asparagine, sodium:proton antiporter activity; L-glutamine, sodium:proton antiporter activity; and L-histidine, sodium:proton antiporter activity. Involved in carboxylic acid transport and intracellular amino acid homeostasis. Acts upstream of or within several processes, including carboxylic acid transport; cellular response to potassium ion starvation; and response to acidic pH. Located in apical plasma membrane. Is expressed in several structures, including central nervous system; metanephros; pancreas; pericardium; and retina. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 102. Orthologous to human SLC38A3 (solute carrier family 38 member 3). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • sodium-coupled neutral amino acid transporter 3
  • N system amino acids transporter NAT-1
  • N-system amino acid transporter 1
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Properties