| Protein Name | Dicer-1 |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 42693 |
| Gene Symbol | Dcr-1 |
| UniProt | Q9VCU9 (DCR1_DROME), A0A515MFY5 (A0A515MFY5_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
8
Total Number of Articles : 9 |
Description |
Dicer-1 |
| Gene Summary |
Enables pre-miRNA binding activity; ribonuclease III activity; and single-stranded RNA binding activity. Involved in several processes, including germ cell development; pole cell formation; and regulatory ncRNA-mediated gene silencing. Located in cytosol and nucleus. Part of RISC-loading complex. Is expressed in spermatozoon. Human ortholog(s) of this gene implicated in DICER1 syndrome; gastrointestinal system cancer (multiple); multinodular goiter; nephroma; and pleuropulmonary blastoma. Orthologous to human DICER1 (dicer 1, ribonuclease III). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |