Protein Name MAP-kinase activating death domain
Organism Mus musculus
Gene ID 228355
Gene Symbol

Madd

UniProt Q80U28 (MADD_MOUSE), E9QN47 (E9QN47_MOUSE), A2AGR0 (A2AGR0_MOUSE), A0A0R4J1F4 (A0A0R4J1F4_MOUSE)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 2
Description

MAP-kinase activating death domain

Gene Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in anterograde synaptic vesicle transport; execution phase of apoptosis; and regulation of cell cycle. Acts upstream of or within negative regulation of apoptotic signaling pathway. Predicted to be located in plasma membrane and synaptic vesicle. Predicted to be active in cytosol and synapse. Is expressed in cerebral cortex; nervous system; sensory organ; and tongue. Used to study type 2 diabetes mellitus. Orthologous to human MADD (MAP kinase activating death domain). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • MAP kinase-activating death domain protein
  • Rab3 GDP/GTP exchange protein
  • Rab3 GEP
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Properties