Protein Name RP2 activator of ARL3 GTPase
Organism Homo sapiens
Gene ID 6102
Gene Symbol

RP2

UniProt O75695 (XRP2_HUMAN), A0A1B2JLU2 (A0A1B2JLU2_HUMAN)
Relationships Total Number of functionally related compound(s) : 79
Total Number of Articles : 58
Description

RP2 activator of ARL3 GTPase

Gene Summary

The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death [provided by RefSeq, Jul 2008]

synonyms
  • protein XRP2
  • RP2, ARL3 GTPase activating protein
  • retinitis pigmentosa 2 (X-linked recessive)
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Properties