Protein Name NLR family, pyrin domain containing 1B
Organism Mus musculus
Gene ID 637515
Gene Symbol

Nlrp1b

UniProt A1Z198 (NL1B2_MOUSE)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 7
Description

NLR family, pyrin domain containing 1B

Gene Summary

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and cysteine-type endopeptidase activator activity. Acts upstream of or within protein catabolic process and pyroptotic inflammatory response. Predicted to be located in nucleoplasm. Predicted to be part of NLRP1 inflammasome complex and NLRP3 inflammasome complex. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in vitiligo. Orthologous to human NLRP1 (NLR family pyrin domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • NACHT, LRR and PYD domains-containing protein 1b allele 2
  • NACHT, LRR and PYD domains-containing protein 1b
  • NACHT-, LRR-, and PYD-containing protein 1 paralog b
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Properties